Investigator Initiated Research (IIR)

EVICR.net is a platform for multinational clinical research in Ophthalmology in Europe and a structure to support multinational Investigator-Initiated Research (IIR). IIR are studies instigated by academic researchers.

If you are an Investigator and you have an idea for a multinational clinical study, EVICR.net helps you to develop your idea in a clinical research study in ophthalmology.

Consult the EVICR.net Investigator Initiated Research (IIR) leaflet for further information.


Ongoing Investigator Initiated Research

 

1. ClinicalTrials.gov nº NCT06709339

MONDEGO – A phase IV, multicentre, open-label, single-arm study to investigate the efficacy, safety and durability of faricimab (RO6867461) in caucasian patients with polypoidal choroidal vasculopathy”

Coordinating Investigator: Rufino Silva, Coimbra, Portugal (CS82)

Participating Centres (30): Italy, Portugal, Spain and UK.

Sponsor: AIBILI, as EVICR.net Coordinating Centre

Financial Support: Roche

 

2. ClinicalTrials.gov nº NCT05698316

INTERCEPT-AMD – A collaborative resource of Heidelberg multimodal imaging of Intermediate AMD with and without early atrophy to study prediction of disease progression

Coordinating Investigator: Sobha Sivaprasad, London, UK (CS10)

Participating Centres (20): Denmark, France, Germany, Italy, Netherlands, Portugal, Spain, Switzerland, United Kingdom

Sponsor: AIBILI, as EVICR.net Coordinating Centre

Financial Support: Boehringer Ingelheim International GmbH

 

3. ClinicalTrials.gov ID: NCT04636307

CHART – Characterization of Retinal Disease Progression in Eyes With NPDR in Diabetes Type 2 Using Non-invasive Procedures

Coordinating Investigator: J. Cunha-Vaz (CS 1)

Characterisation of Biomarkers of Diabetic Retinal Disease Progression in eyes with NPDR using non-invasive procedures.

Participating Centres (5): Portugal, Italy,  France

IIR Grant: Bayer

 

4. ClinicalTrials.gov nº NCT04281186

RECOGNISED –Retinal and Cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of dementia

Coordinating Investigator: R. Simó, Barcelona, Spain (CS74)

Participating Centres (10): Denmark, Italy, Netherlands, Portugal, Spain and UK

Sponsor: Fundació Hospital Universitari Vall D’Hebron, VHIR, represented by Prof. Rafael Simó.

Financial Support:  Horizon 2020 – Project nº 847749

 

5. ClinicalTrials.gov nº NCT03349801

MACUSTAR – Intermediate AMD: Development of novel clinical endpoints for clinical trials in patients with a regulatory and patient access intention

Coordinating Investigator: Frank Holz, Bonn, Germany (CS15)

Participating Centres (20): Denmark, France, Germany, Italy, Netherlands, Portugal, United Kingdom

Sponsor: University Hospital Bonn

Financial Support: IMI2 and EFPIA – Project nº 116076

Positioning at the Ophthalmology Research in Europe

EVICR.net serves as a fundamental resource for the development of translational research and particularly Pharmaceutical and Medical Devices Innovation in the European Union in Ophthalmology.