Investigator Initiated Research (IIR)

EVICR.net is a platform for multinational clinical research in Ophthalmology in Europe and a structure to support multinational Investigator-Initiated Research (IIR). IIR are studies instigated by academic researchers.

If you are an Investigator and you have an idea for a multinational clinical study, EVICR.net helps you to develop your idea in a clinical research study in ophthalmology.

Consult the EVICR.net Investigator Initiated Research (IIR) leaflet for further information.


Ongoing Investigator Initiated Research

 

1.EudraCT nº 2012-001200-38
ClinicalTrials.gov nº NCT01726075

EUROCONDOR – Neurodegeneration as an early event in the pathogenesis of Diabetic Retinopathy: A multicentric, prospective, phase II-III, double-blind randomized controlled trial to assess the efficacy of neuroprotective drugs administered topically to prevent or arrest Diabetic Retinopathy

Project Coordinator: Rafael Simó, Barcelona, Spain

Coordinating Investigator: José Cunha-Vaz, Coimbra, Portugal (CS1)

Participating Centres (11): Barcelona, Birmingham, Cheltenham, Coimbra, Liverpool, London, Milan, Odense, Padova, Paris, Ulm

Financial Support: European Union 7th Framework Programme – Call Health 2011 – Project nº 278040-2

 

2. ClinicalTrials.gov nº NCT02495181

EudraCT nº 2015-001368-20

ATLANTIC – A Randomized, Double-masked, Sham-controlled Phase 4 Study of the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Monotherapy Compared to Aflibercept with Adjunctive Photodynamic Therapy in patients with Polypoidal Choroidal Vasculopathy

Coordinating Investigator: Rufino Silva, Coimbra, Portugal (CS82)

Participating Centres (18): Albacete, Barcelona (4), Braga, Coimbra (2), Las Palmas, Leiria, Lisbon (4), Oviedo, Porto (2), Vila Franca de Xira

IIR Grant: Bayer

 

3. ClinicalTrials.gov nº NCT03235856

REDCAKE – Retrospective Digital Computer Analysis of Keratoconus Evolution

Coordinating Investigator: Jos Rozema, Antwerp, Belgium (CS12)

Participating Centres (13): Belgium, Germany, Italy, Spain, Switzerland, Netherlands, Portugal

Sponsor: Antwerp University Hospital

IIR Grant: Flemish Fund for Research

 

4. ClinicalTrials.gov nº NCT03349801

MACUSTAR – Intermediate AMD: Development of novel clinical endpoints for clinical trials in patients with a regulatory and patient access intention

Coordinating Investigator: Frank Holz, Bonn, Germany (CS15)

Participating Centres (20): Denmark, France, Germany, Italy, Netherlands, Portugal, United Kingdom

Sponsor: University Hospital Bonn

Financial Support: IMI2 and EFPIA – Project nº 116076

 

Other ongoing Investigator Initiated Research

 

1. ClinicalTrials.gov nº NCT03297515

MADEOS – Prospective, randomised, double-blind study to assess the Therapeutic Potential of Omega-3 Fatty Acids Supplementation in Dry Macular Degeneration and Stargardt Disease (Macular Degeneration Omega-3 Study

Participating Centres (5): France (1), Germany (1), Italy (3)

Sponsor: Ophthalmos Research and Educational Institute

Positioning at the Ophthalmology Research in Europe

EVICR.net serves as a fundamental resource for the development of translational research and particularly Pharmaceutical and Medical Devices Innovation in the European Union in Ophthalmology.